Sickle cell anemia research paper

Healthy red blood cells are flexible so that they can move through the smallest blood vessels. However, there are treatments that help people manage and live with the disease. They may include: There are no standard treatments that cure sickle cell anemia. Rarely, extreme conditions such as severe dehydration and high-intensity physical activity can lead to serious health issues, including sudden death, in individuals with sickle cell trait. Learn More about Sickle Cell Trait   Sickle cell anemia is more common in certain ethnic groups, including: Because sickle cell anemia symptoms can begin by four months of age, early diagnosis is critical. If you have sickle cell disease, you will pass one sickle cell gene to your children. Sickle cell trait is an inherited blood disorder that affects approximately 8 percent of African-Americans. Depending on your condition, your doctor may refer you to a hematologist, a doctor who specializes in blood conditions. Since researchers first identified sickle cell disease more than 655 years ago, numerous advances have been made in the  treatment and care  of sickle cell patients. Read the latest  clinical sickle cell disease research published in  Blood, the official journal of ASH.

If you carry the sickle cell trait, make sure you tell your doctor before getting pregnant as well. Read more about sickle cell trait  here. Researchers are looking at new drugs and also exploring the use of  bone marrow transplants  to treat sickle cell disease. Treatment relieves pain, prevents infections, minimizes organ damage, and controls complications and can include medications, such as pain relievers and hydroxyurea (Hydrea), at times blood transfusions, and other options as needed. Clinical trials  provide access to experimental therapies for treating sickle cell anemia. Urge your members of Congress to support continued medical research fundingApproximately 75,555-655,555 Americans have sickle cell anemia, the most common form of an inherited blood disorder that causes the production of abnormal hemoglobin, a protein that attaches to oxygen in the lungs and carries it to all parts of the body. ASH provides information on clinical trials for which you may be eligible. Unlike sickle cell disease, in which patients have two genes that cause the production of abnormal hemoglobin, individuals with sickle cell trait carry only one defective gene and typically live normal lives without health problems related to sickle cell. People who carry the sickle cell gene can seek genetic counseling before pregnancy to discuss options. Signs and symptoms of sickle cell anemia can be mild or severe enough to require frequent hospitalizations.

All newborns in the United States are now tested for the disease. There are variations of sickle cell disease called sickle C or sickle thalassemia, which are serious conditions but are sometimes less severe. In sickle cell anemia, the hemoglobin is abnormal, causing the red blood cells to be rigid and shaped like a C or sickle, the shape from which the disease takes its name. Complications of sickle cell anemia are a result of sickle cells blocking blood flow to specific organs, and include stroke, acute chest syndrome (a condition that lowers the level of oxygen in the blood), organ damage, other disabilities, and in some cases premature death. In order for you or your child to inherit sickle cell anemia,  both  parents must have either sickle cell anemia (two sickle cell genes) or sickle cell trait (one sickle cell gene) Sickle cell anemia can be identified before birth by testing a sample of amniotic fluid or tissue from the placenta. Stem cell transplants are associated with significant risks and are appropriate only for some patients with severe forms of sickle cell disease and closely matched donors such as a family member. It is important for you to talk with your doctor if you believe you may have sickle cell anemia. Sickle cells can get stuck and block blood flow, causing pain and infections. Sickle cell anemia research paper.